Pristiq Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Pristiq:

Constipation; decreased sexual desire or ability; diarrhea; dizziness; drowsiness; dry mouth; fatigue; flushing; headache; increased sweating; loss of appetite; nausea; stomach upset; trouble sleeping; vomiting; yawning.

Seek medical attention right away if any of these SEVERE side effects occur when using Pristiq:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); behavior changes; blood in the stools; blurred vision; chest pain or discomfort; confusion; decreased concentration; decreased coordination; decreased urination; enlarged pupils; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; memory problems; new or worsening agitation, anxiety, panic attacks, aggressiveness, impulsiveness, irritability, hostility, restlessness, or inability to sit still; new or worsening mental or mood changes; red, swollen, blistered, or peeling skin; seizures; severe or persistent cough; severe or persistent headache, dizziness, or stomach pain; severe or persistent trouble sleeping; shortness of breath; significant weight loss; suicidal thoughts or attempts; tremor; unusual bruising or bleeding; unusual weakness; worsening of depression.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.